Key result
English bulldogs with presumed arrhythmogenic right ventricular cardiomyopathy frequently presented with arrhythmias or heart failure and had a median survival time of 8.3 months.
Observational (n=31)
This study provides the first clinical description of presumed ARVC in English bulldogs, demonstrating a high prevalence of ventricular arrhythmias and heart failure with a median survival of 8.3 months.
Highlights short median survival in English bulldogs with presumed ARVC; leaves open optimal management pending larger studies.
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an important cause of sudden death in people and boxer dogs that has recently been described in English bulldogs. The objective of this retrospective study was to describe the clinical characteristics of English bulldogs with presumed ARVC. The medical records were searched for English bulldogs examined between 2001 and 2013 with a clinical diagnosis of ARVC. The average age of the 31 dogs identified was 9.2 ± 1.6 yr (range 7-13 yr). Males were overrepresented by a factor of 2.9 to 1. At initial presentation, 5 dogs had subclinical arrhythmia, 10 dogs had clinical signs attributable to arrhythmia, and 16 dogs had congestive heart failure. Eighteen dogs (58%) had ventricular tachycardia and five (16%) also had supraventricular arrhythmias. Four dogs experienced sudden death, 2 dogs died from congestive heart failure, 11 dogs were euthanized for cardiac causes, and 2 dogs died or were euthanized for noncardiac causes. Kaplan-Meier analysis showed a median survival time of 8.3 mo. This is the first study to describe the clinical characteristics of a population of English bulldogs with presumed ARVC. Further studies are needed to better characterize the clinical features of the disease in this breed.
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Cunningham et al. (2018) conducted an observational in Arrhythmogenic right ventricular cardiomyopathy (n=31). Arrhythmogenic right ventricular cardiomyopathy was evaluated on Survival time. English bulldogs with presumed arrhythmogenic right ventricular cardiomyopathy frequently presented with arrhythmias or heart failure and had a median survival time of 8.3 months.
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