Why the study?
Does adjuvant recombinant interferon alfa-2b improve overall and event-free survival in patients with Robson stages II and III renal cell carcinoma after radical nephrectomy?
Population
247 patients with Robson stages II and III renal cell carcinoma after radical nephrectomy
Comparison
Adjuvant recombinant interferon alfa-2b vs Observation
Design
RCT, randomized
Follow-up
5 years
Authors
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Adjuvant interferon alfa-2b should not be used after nephrectomy for Robson II-III RCC; confirms no survival benefit in this RCT.
Does adjuvant recombinant interferon alfa-2b improve overall and event-free survival in patients with Robson stages II and III renal cell carcinoma after radical nephrectomy?
Adjuvant recombinant interferon alfa-2b does not improve overall or event-free survival after radical nephrectomy for Robson stages II and III renal cell carcinoma and is not indicated.
Pizzocaro et al. (2001) studied this question.
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