Key result
Measurement of the CO single breath transfer factor and its components offers a reliable guide for establishing cardiac pump efficacy and following up therapy in valvular heart disease.
Why the study?
Does the measurement of CO single breath transfer factor of the lung (Tv) and its components (Dmv and Vcv) provide a reliable guide for establishing cardiac pump efficacy in patients with valvular heart disease?
Observational (n=46)
Does the measurement of CO single breath transfer factor of the lung (Tv) and its components (Dmv and Vcv) provide a reliable guide for establishing cardiac pump efficacy in patients with valvular heart disease?
Measurement of the CO single breath transfer factor and its components provides a reliable physiological guide for assessing cardiac pump efficacy in valvular heart disease.
Answers are grounded in this paper and cite their sources.
May support pump assessment in valvular disease; leaves open prospective validation before clinical use.
The CO single breath transfer factor of the lung expressed per unit of alveolar gas volume during breath-holding, Tv, and its component factors Dmv and Vcv have been determined in 46 patients suffering from valvular heart disease. It has been shown that Tv cannot be correctly interpreted, unless the values of Dmv and Vcv are known. The results of measurements of gas transfer using this method offer a reliable guide for establishing the efficacy of the cardiac pump, and for following up the effect of therapy in valvular heart disease.
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Werner et al. (2009) conducted an observational in Valvular heart disease (n=46). CO single breath transfer factor measurement was evaluated on CO single breath transfer factor (Tv) and its component factors Dmv and Vcv. Measurement of the CO single breath transfer factor and its components offers a reliable guide for establishing cardiac pump efficacy and following up therapy in valvular heart disease.
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