Key result
At low frequencies and high mean pressures, forward transmission of pressure waves was several times greater than backward transmission (transmission ratio >1).
Population
Anesthetized open-chest dogs
Comparison
Snaring lobar vessels and infusing dextran to… vs Baseline
Design
Preclinical
Authors
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May refine pulmonary wedge pressure interpretation in monitoring; leaves open translation to human disease.
The study demonstrates that in the pulmonary vascular bed, forward transmission of pressure waves exceeds backward transmission at low frequencies and high mean pressures, likely due to higher arterial compliance, providing insight into arterial wedge-pressure traces.
Bergel et al. (1967) studied this question. Dextran infusion and snaring lobar vessels vs. Baseline (before intervention) was evaluated on Forward and backward transmission of pressure waves. At low frequencies and high mean pressures, forward transmission of pressure waves was several times greater than backward transmission (transmission ratio >1).
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