What is the clinical evidence from this study?

Study design: Case Report. Population: Torsade de pointes (n=2). Intervention: Transvenous pacing vs. Conventional antiarrhythmic drugs. Primary outcome: Suppression of tachycardia.

What question did this study set out to answer?

Describe the clinical presentation, electrocardiographic hallmarks, and management strategies for syncope caused by torsade de pointes associated with atrioventricular block.

September 1, 1980Archives of Internal Medicine

Torsade de Pointes

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Key result

Increasing the heart rate by transvenous pacing completely suppressed the tachycardia in two patients with torsade de pointes.

Why the study?

Does transvenous pacing suppress tachycardia in patients with torsade de pointes?

Population

2 patients with syncope due to atypical ventricular tachycardia associated with high-degree atrioventricular…

Comparison

Transvenous pacing to increase heart rate vs Conventional antiarrhythmic drugs

Design

Case_series

Authors

USUrs P. SteinbrecherUniversity of British Columbia

Discussion

Member takes

Implication

Pacing may suppress torsade de pointes in select cases; leaves open confirmation in controlled trials before broader adoption.

Key Points

Describe the clinical presentation, electrocardiographic hallmarks, and management strategies for syncope caused by torsade de pointes associated with atrioventricular block.
Clinical evaluation and electrophysiologic monitoring of two patients (N=2) presenting with syncope and atypical ventricular tachycardia.
Assessment of patient responses to conventional antiarrhythmic drug therapy, transvenous ventricular pacing, and electrolyte correction.
Conventional antiarrhythmic medications failed to terminate or control the atypical ventricular tachycardia in both patients.
Accelerating heart rate via transvenous pacing completely suppressed torsade de pointes episodes in both cases.
QT interval prolongation normalized with pacing alone in one patient, while the other required both pacing and repletion of coexisting hypokalemia.

Study Design

Type

Case Report (n=2)

Structured PICO

Does transvenous pacing suppress tachycardia in patients with torsade de pointes?

Population

Two patients with syncope due to atypical ventricular tachycardia (torsade de pointes).

Intervention

Transvenous pacing to increase heart rate

Comparator

Conventional antiarrhythmic drugs

Outcome

Suppression of tachycardia

Transvenous pacing effectively suppresses torsade de pointes, highlighting the importance of increasing heart rate and correcting underlying causes rather than using conventional antiarrhythmic drugs.

Cite This Study

Urs P. Steinbrecher (1980) conducted a case report in Torsade de pointes (n=2). Transvenous pacing vs. Conventional antiarrhythmic drugs was evaluated on Suppression of tachycardia. Increasing the heart rate by transvenous pacing completely suppressed the tachycardia in two patients with torsade de pointes.

synapsesocial.com/papers/6a92af43cfe2d75514a6098c https://doi.org/10.1001/archinte.1980.00330200099027

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Torsade de Pointes

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Torsade de Pointes

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Also Consider

Also Consider