Key result
Coxsackie virus Group A Types 20, 21, and 23 were cytopathogenic in tissue cultures, whereas Types 22 and 24 did not induce damage on any of the cell types used.
Population
Suckling mice and tissue cultures used for isolation of Coxsackie virus Group A Types 20-24
Design
Preclinical
Authors
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These culture preferences may refine lab isolation protocols; leaves open relevance to human enteroviral diagnostics or disease models.
The study identifies new types of Coxsackie virus Group A and characterizes their isolation preferences and cytopathogenicity in tissue cultures versus suckling mice.
Sickles et al. (1959) studied Coxsackie virus Group A. Coxsackie virus Group A Types 20, 21, and 23 were cytopathogenic in tissue cultures, whereas Types 22 and 24 did not induce damage on any of the cell types used.
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