Key result
Intravenous digoxin administration in patients with ventricular failure intensified splanchnic vasoconstriction, diminishing splanchnic blood flow and volume while systemic flow rose.
Why the study?
Does intravenous digoxin alter splanchnic hemodynamics in patients with ventricular failure?
Population
22 patients with heart disease, 16 of whom had evidence of ventricular insufficiency
Design
Case_series
Authors
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May indicate splanchnic vasoconstriction with IV digoxin in ventricular failure; hypothesis-generating and should not change practice.
Observational (n=22)
Does intravenous digoxin alter splanchnic hemodynamics in patients with ventricular failure?
Intravenous digoxin reduces splanchnic blood volume and flow in patients with ventricular failure, suggesting a redistribution of blood to the systemic circulation.
FERRER et al. (1965) conducted an observational in Heart disease with ventricular failure (n=22). Intravenous digoxin was evaluated on Splanchnic hemodynamics (splanchnic blood flow, splanchnic blood volume, and peripheral vascular resistance). Intravenous digoxin administration in patients with ventricular failure intensified splanchnic vasoconstriction, diminishing splanchnic blood flow and volume while systemic flow rose.
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