Key result
In a computational model, an ascending aortic aneurysm had a maximum blood velocity 1.6 times lower (1.18 vs 1.9 m/s) and 45% greater wall displacement compared to a healthy aorta.
Why the study?
Understanding blood flow mechanics through numerical modelling can be crucial in identifying connections between haemodynamic factors and aortic wall pathologies.
Computational modeling reveals that ascending aortic aneurysms exhibit significantly altered hemodynamics, including reduced blood velocity and increased wall displacement, which may contribute to understanding aortic wall pathologies.
BACKGROUND: The usefulness of numerical modelling of a patient's cardiovascular system is growing in clinical treatment. Understanding blood flow mechanics can be crucial in identifying connections between haemodynamic factors and aortic wall pathologies. OBJECTIVE: This work investigates the haemodynamic parameters of an ascending aorta and ascending aortic aneurysm in humans. METHODS: Two aortic models were constructed from medical images using the SimVascular software. FEM blood flow modelling of cardiac cycle was performed using CFD and CMM-FSI at different vascular wall parameters. RESULTS: The results showed that highest blood velocity was 1.18 m/s in aorta with the aneurysm and 1.9 m/s in healthy aorta model. The largest displacements ware in the aorta with the aneurysm (0.73 mm). In the aorta with the aneurysm, time averaged WSS values throughout the artery range from 0 Pa to 1 Pa. In the healthy aorta, distribution of WSS values changes from 0.3 Pa to 0.6 Pa. CONCLUSIONS: In the case of an ascending aortic aneurysm, the maximum blood velocity was found to be 1.6 times lower than in the healthy aorta. The aneurysm-based model demonstrates a 45% greater wall displacement, while the oscillatory shear index decreased by 30% compared to healthy aortic results.
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A 2021 study studied Ascending aortic aneurysm (n=2). Ascending aortic aneurysm vs. Healthy aorta was evaluated on Maximum blood velocity (m/s). In a computational model, an ascending aortic aneurysm had a maximum blood velocity 1.6 times lower (1.18 vs 1.9 m/s) and 45% greater wall displacement compared to a healthy aorta.
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