Key result
Fine-needle aspiration biopsy initially misidentified angiosarcoma of the breast as granulation tissue, highlighting a diagnostic pitfall that was corrected on repeat biopsy 4 months later.
Case Report (n=1)
This case report highlights the cytological features and potential pitfalls in diagnosing angiosarcoma of the breast using fine-needle aspiration.
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Clinicians should pursue repeat biopsy if suspicion for breast angiosarcoma persists after benign FNA; case reports leave open optimal diagnostic strategies.
This paper describes a case of angiosarcoma of the breast in a 26-yr-old female. The tumor, originally thought to be granulation tissue on fine-needle aspiration biopsy, was correctly identified as a malignant neoplasm of probable mesenchymal origin on a repeat FNA biopsy 4 mo later. A diagnosis of angiosarcoma was made on a subsequent excisional biopsy. Review of the cytologic features revealed findings that should suggest angiosarcoma, especially when correlated with the clinical history. The authors describe the cytological features seen in this case, and discuss an important pitfall in the diagnosis of angiosarcoma of the breast on FNA.
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Carson et al. (1994) conducted a case report in Angiosarcoma of the breast (n=1). Fine-needle aspiration biopsy was evaluated on Cytologic diagnosis of angiosarcoma. Fine-needle aspiration biopsy initially misidentified angiosarcoma of the breast as granulation tissue, highlighting a diagnostic pitfall that was corrected on repeat biopsy 4 months later.
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