Population
HEK-293 cells transiently transfected with human alpha (Ca3.1), alpha (Ca3.2) and alpha (Ca3.3) subunits…
Comparison
Expression of specific T-type calcium channel… vs Comparison among the different isotypes
Design
Preclinical
Authors
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Channel isotype-specific gating may shape neuronal firing patterns; hypothesis-generating for T-type roles in cardiac automaticity.
Different human T-type calcium channel isotypes display specific gating properties that uniquely contribute to neuronal firing patterns, with alpha(1I) playing a role in pacemaker activity.
Chemin et al. (2002) studied this question.
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