Key result
Isobaric levobupivacaine significantly prolonged the duration of motor blockade (197.74 vs 131.88 minutes) compared to isobaric ropivacaine in patients undergoing lower abdominal and lower limb surgeries.
Why the study?
Does isobaric levobupivacaine compared to isobaric ropivacaine improve sensory and motor block characteristics in patients undergoing lower abdominal and lower limb surgeries?
Population
68 ASA I-II adult patients of either sex scheduled for elective lower abdominal and lower limb surgeries…
Comparison
Isobaric levobupivacaine 0.5% 3ml administered… vs Isobaric ropivacaine 0.5% 3ml administered…
Design
RCT, Randomly divided by sealed envelope method into 2 groups, Double blind
Follow-up
Until complete recovery of sensory and motor block
Authors
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Levobupivacaine favors longer motor blockade than ropivacaine for lower abdominal/limb surgeries; extends RCT comparisons of isobaric agents.
RCT (n=68)
Double-blind
Sealed envelope method
No
Does isobaric levobupivacaine compared to isobaric ropivacaine improve sensory and motor block characteristics in patients undergoing lower abdominal and lower limb surgeries?
Absolute Event Rate: 197.74% vs 131.88%
p-value: p=<0.001
Isobaric levobupivacaine provides a significantly longer duration of motor and sensory blockade compared to isobaric ropivacaine, making it a suitable option for prolonged lower abdominal and lower limb surgeries.
Hoda et al. (2018) conducted an RCT in Elective lower abdominal and lower limb surgeries (n=68). Isobaric levobupivacaine vs. Isobaric ropivacaine 3ml of 0.5% (15mg) was evaluated on Duration of motor blockade (minutes) (p=<0.001). Isobaric levobupivacaine significantly prolonged the duration of motor blockade (197.74 vs 131.88 minutes) compared to isobaric ropivacaine in patients undergoing lower abdominal and lower limb surgeries.
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