Key result
Epidural levobupivacaine 0.5% and ropivacaine 0.75% provided comparable sensory and motor blockade characteristics, with no significant difference in the mean onset time of sensory blockade (10.0 vs 9.0 minutes).
Why the study?
Does epidural levobupivacaine 0.5% provide similar sensory and motor block characteristics compared to ropivacaine 0.75% in adults undergoing lower abdominal surgeries?
Population
100 adult patients undergoing lower abdominal surgeries.
Comparison
Levobupivacaine 0.5% in epidural route in a… vs Ropivacaine 0.75% in epidural route in a volume…
Design
RCT, allocated randomly into groups by lottery method, double blind
Follow-up
Intraoperative and immediate postoperative period
Authors
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Either agent may be chosen for lower abdominal epidural anesthesia based on availability or cost; reinforces equivalence in this RCT.
RCT (n=100)
Double-blind
Lottery method
No
Does epidural levobupivacaine 0.5% provide similar sensory and motor block characteristics compared to ropivacaine 0.75% in adults undergoing lower abdominal surgeries?
Absolute Event Rate: 10% vs 9%
p-value: p=not significant
Epidural levobupivacaine 0.5% and ropivacaine 0.75% provide clinically similar sensory and motor blockade with minimal side effects for lower abdominal surgeries.
Kiran et al. (2016) conducted an RCT in Lower abdominal surgeries (n=100). Levobupivacaine vs. 20 ml of 0.75% Ropivacaine was evaluated on Mean time of onset of sensory blockade to T10 level (minutes) (p=not significant). Epidural levobupivacaine 0.5% and ropivacaine 0.75% provided comparable sensory and motor blockade characteristics, with no significant difference in the mean onset time of sensory blockade (10.0 vs 9.0 minutes).
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