Key result
Epidural 0.5% ropivacaine provided a significantly longer duration of sensory block (257.66 vs 222 minutes, p<0.001) and shorter duration of motor block compared to 0.5% bupivacaine.
Why the study?
Does epidural ropivacaine 0.5% improve sensory and motor block characteristics and postoperative analgesia compared to bupivacaine 0.5% in patients undergoing lower limb orthopaedic surgeries?
RCT (n=60)
Double-blind
Computer generated random number
No
Does epidural ropivacaine 0.5% improve sensory and motor block characteristics and postoperative analgesia compared to bupivacaine 0.5% in patients undergoing lower limb orthopaedic surgeries?
Absolute Event Rate: 257.66% vs 222%
p-value: p=<0.001
Epidural ropivacaine 0.5% provides faster onset and prolonged duration of sensory block, shorter duration of motor block, and prolonged postoperative analgesia compared to bupivacaine 0.5% in lower limb orthopedic surgeries.
Authors
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Supports preferring epidural ropivacaine 0.5% in lower limb orthopedic surgery; extends RCT evidence favoring it over bupivacaine.
Shah et al. (2017) conducted an RCT in Lower limb orthopaedic surgeries (n=60). Ropivacaine vs. Bupivacaine 0.5% (20 ml) was evaluated on Duration of sensory block (minutes) (p=<0.001). Epidural 0.5% ropivacaine provided a significantly longer duration of sensory block (257.66 vs 222 minutes, p<0.001) and shorter duration of motor block compared to 0.5% bupivacaine.
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