Key result
Normalized TAPSE significantly decreased in dogs with severe pulmonary hypertension (P < .05), and the TAPSE B-mode/RVIDd ratio independently predicted right-sided congestive heart failure.
Why the study?
TAPSE is load, angle, and body weight dependent and does not decrease in dogs with MMVD and postcapillary PH, prompting evaluation of TAPSE normalized by RV size.
Does TAPSE normalized by RV size indices better predict right-sided congestive heart failure compared to nonnormalized TAPSE in dogs with postcapillary pulmonary hypertension?
Observational (n=91)
Does TAPSE normalized by RV size indices better predict right-sided congestive heart failure compared to nonnormalized TAPSE in dogs with postcapillary pulmonary hypertension?
p-value: p=<.05
Normalizing TAPSE by right ventricular size indices improves the detection of RV systolic dysfunction and prediction of right-sided congestive heart failure in dogs with severe pulmonary hypertension.
No takes yet. Share an insight, caveat, or question.
May enhance RV dysfunction detection in canine severe PH; extends TAPSE metrics but leaves open prospective validation of superiority.
Yuchi et al. (2020) conducted an observational in Myxomatous mitral valve disease and postcapillary pulmonary hypertension (n=91). Normalized TAPSE (TAPSE divided by RV size indices) vs. Nonnormalized TAPSE was evaluated on Decrease in normalized TAPSE in the severe PH group (p=<.05). Normalized TAPSE significantly decreased in dogs with severe pulmonary hypertension (P < .05), and the TAPSE B-mode/RVIDd ratio independently predicted right-sided congestive heart failure.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: