Key result
Severe pulmonary hypertension in dogs was associated with a significantly higher right ventricular end-diastolic area index (12.4 cm2/m2) compared to healthy controls (8.5 cm2/m2; P < 0.001).
Why the study?
Does echocardiographic evaluation of RV dimension and systolic function correlate with disease severity and right-sided congestive heart failure in dogs with pulmonary hypertension?
Population
89 dogs with pulmonary hypertension (PH) and 74 healthy dogs
Comparison
Echocardiographic evaluation of right… vs Healthy dogs and dogs with varying degrees of PH…
Design
Preclinical
Authors
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Supports RVEDA index for RV size assessment in canine PH; hypothesis-generating and requires prospective validation before clinical use.
Observational (n=163)
Does echocardiographic evaluation of RV dimension and systolic function correlate with disease severity and right-sided congestive heart failure in dogs with pulmonary hypertension?
Absolute Event Rate: 12.4% vs 8.5%
p-value: p=<.001
The RVEDA index is a useful echocardiographic parameter to evaluate RV size and predict right-sided congestive heart failure in dogs with pulmonary hypertension.
Vezzosi et al. (2018) conducted an observational in Pulmonary hypertension (n=163). Pulmonary hypertension vs. Healthy dogs was evaluated on Right ventricular end-diastolic area (RVEDA) index (p=<.001). Severe pulmonary hypertension in dogs was associated with a significantly higher right ventricular end-diastolic area index (12.4 cm2/m2) compared to healthy controls (8.5 cm2/m2; P < 0.001).
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