Key result
In dogs with myxomatous mitral valve disease, a high probability of pulmonary hypertension was associated with right ventricular myocardial dysfunction and dilatation, while increased RV MPI and RVIDd index were significantly associated with right-sided congestive heart failure.
Why the study?
Pulmonary hypertension commonly complicates myxomatous mitral valve disease in dogs and can alter right heart structure, but whether RV systolic and diastolic function worsen with PH progression was unclear.
Does two-dimensional speckle tracking echocardiography detect right ventricular systolic and diastolic dysfunction in dogs with myxomatous mitral valve disease and pulmonary hypertension?
Comparison
Dogs with MMVD stratified by probability of PH vs healthy dogs
Design
Observational comparative study
Authors
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RV indices may flag right-sided CHF risk in MMVD dogs with PH; hypothesis-generating and requires prospective validation.
Observational (n=83)
Single-blind
No
Does two-dimensional speckle tracking echocardiography detect right ventricular systolic and diastolic dysfunction in dogs with myxomatous mitral valve disease and pulmonary hypertension?
Two-dimensional speckle tracking echocardiography reveals that dogs with myxomatous mitral valve disease and a high probability of pulmonary hypertension have significant right ventricular systolic and diastolic dysfunction.
Yuchi et al. (2021) conducted an observational in Myxomatous mitral valve disease and pulmonary hypertension (n=83). Myxomatous mitral valve disease with varying probabilities of pulmonary hypertension vs. Healthy dogs was evaluated on Right ventricular systolic and diastolic function assessed by echocardiographic indices. In dogs with myxomatous mitral valve disease, a high probability of pulmonary hypertension was associated with right ventricular myocardial dysfunction and dilatation, while increased RV MPI and RVIDd index were significantly associated with right-sided congestive heart failure.
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