Why the study?
Does cardiopulmonary bypass affect platelet count and function, and does this impact bleeding in patients undergoing cardiac surgery?
Does cardiopulmonary bypass affect platelet count and function, and does this impact bleeding in patients undergoing cardiac surgery?
Cardiopulmonary bypass reduces platelet count and aggregation, contributing to increased postoperative bleeding and highlighting the potential utility of perioperative platelet function monitoring.
May support platelet monitoring to assess bleeding risk; hypothesis-generating for targeted interventions in cardiac surgery.
The results of this study demonstrate that platelet count and platelet aggregation are reduced during CPB. Our results emphasized the effect of platelet dysfunction on increased postoperative bleeding and transfusion requirements. Perioperative monitoring of platelet function can be considered as a bleeding management strategy for implantation of PBM programs.
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Adeli et al. (2017) studied this question.
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