Why the study?
Pediatric patients are prone to CPB-induced coagulopathy, but the role of platelet count and function in post-CPB bleeding risk required investigation.
Does the postoperative reduction in platelet count and function predict major postoperative bleeding in pediatric patients undergoing cardiac surgery with cardiopulmonary bypass?
Does the postoperative reduction in platelet count and function predict major postoperative bleeding in pediatric patients undergoing cardiac surgery with cardiopulmonary bypass?
In pediatric patients undergoing cardiac surgery with cardiopulmonary bypass, a greater postoperative reduction in platelet count and function is predictive of major postoperative bleeding.
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Platelet parameters may identify high bleeding risk after pediatric CPB; leaves open whether they should guide transfusion practice.
Gregorio et al. (2021) studied this question.
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