Key result
Cellular membrane caveolae disarray is proposed as a mechanistic link for the metabolic abnormalities seen in metabolic syndrome, offering a potential new therapeutic target.
Design
Review
Authors
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Does not support caveolae-targeted therapy in metabolic syndrome; leaves open a unifying mechanism requiring prospective validation.
Cellular membrane caveolae may serve as a unifying pathophysiological link and novel therapeutic target for the components of metabolic syndrome.
Wei‐Zheng Zhang (2014) conducted a review in Metabolic syndrome. Caveola disarray was evaluated. Cellular membrane caveolae disarray is proposed as a mechanistic link for the metabolic abnormalities seen in metabolic syndrome, offering a potential new therapeutic target.
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