Key result
This review discusses uncertainties in guidelines for controlling blood pressure and preventing stroke in patients with previous cerebrovascular events, including goal BP and drug class selection.
This review highlights uncertainties in current guidelines regarding blood pressure goals, patient selection, and drug classes for stroke prevention in patients with prior cerebrovascular events.
Guideline uncertainties advise caution in BP targets and agents for secondary stroke prevention; leaves open resolution by dedicated trials.
Hypertension is the most important of the prevalent and modifiable risk factors for stroke. Based on evidence, blood pressure (BP) lowering is recommended in guidelines for the prevention of stroke. However, there are still some uncertainties in the guidelines for controlling BP and preventing stroke in patients with previous cerebrovascular events, such as the goal BP, who to treat and which class of BP-lowering drugs to use. This article discusses these questions by reviewing guidelines and corresponding clinical trials, with the aim of reducing the gap between guidelines and clinical practice.
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Zefeng Tan (2011) conducted a review in Hypertension and stroke prevention. Blood pressure lowering was evaluated. This review discusses uncertainties in guidelines for controlling blood pressure and preventing stroke in patients with previous cerebrovascular events, including goal BP and drug class selection.
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