Key result
Variations in computational fluid dynamics mesh sizes significantly affected hepatic flow distribution (P=0.0002) but not indexed power loss (P=0.069) compared to an in vitro flow loop.
Why the study?
Postoperative Fontan outcomes are linked to cavopulmonary pathway geometry, but in vitro validation of the accuracy and efficiency of CFD simulations for predicting Fontan hemodynamics was needed.
p-value: p=0.0002
CFD simulations for Fontan planning can be accurately validated against in vitro flow loops, though prediction accuracy for hepatic flow distribution is sensitive to mesh size.
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Mesh sensitivity cautions CFD use for Fontan hepatic flow predictions; leaves open standardized validation protocols.
Liu et al. (2022) studied Postoperative Fontan operation (n=10). Computational fluid dynamics (CFD) simulations vs. In vitro flow loop setup with 3D printed models was evaluated on Indexed power loss (iPL) and hepatic flow distribution (HFD) (p=0.0002). Variations in computational fluid dynamics mesh sizes significantly affected hepatic flow distribution (P=0.0002) but not indexed power loss (P=0.069) compared to an in vitro flow loop.