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January 1, 2013Acta chirurgica Belgica

Mitral Regurgitation and Coronary Artery Bypass Surgery: Comparison of Mitral Valve Repair and Replacement

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Key result

Mitral valve repair with concomitant CABG showed no statistically significant difference in in-hospital mortality compared to mitral valve replacement with CABG.

Why the study?

Does mitral valve repair compared to mitral valve replacement improve in-hospital outcomes in patients with mitral regurgitation and ischemic heart disease undergoing concomitant CABG?

Population

75 patients with mitral regurgitation and ischemic heart disease

Comparison

Mitral valve repair with concomitant surgical… vs Mitral valve replacement with concomitant…

Design

Cohort

Follow-up

in-hospital

Authors

ALAleksandra LjubačevIMIgor MedvedMOMaja Oštrić

Discussion

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Overview

Comparable in-hospital mortality supports individualized surgical choice; leaves open whether repair improves other outcomes in randomized settings.

Study Design

Type

Cohort (n=75)

Structured PICO

Does mitral valve repair compared to mitral valve replacement improve in-hospital outcomes in patients with mitral regurgitation and ischemic heart disease undergoing concomitant CABG?

P
Population
75 patients who underwent surgery for mitral regurgitation and ischemic heart disease, comparing mitral valve repair versus replacement with concomitant CABG.
E
Exposure
Mitral valve repair (MVRp) with concomitant surgical revascularization of the myocardium (CABG)
C
Comparator
Mitral valve replacement (MVR) with concomitant surgical revascularization of the myocardium (CABG)
O
Outcome
Duration of surgery, early postoperative morbidity, in-hospital mortality, length of stay in the Intensive Care Unit (ICU) and overall in-hospital stayhard clinical

Mitral valve repair and replacement have comparable in-hospital mortality when performed with CABG, though baseline patient risk heavily influences postoperative morbidity and length of stay.

Limitations

  • Baseline differences between groups (MVR + CABG group had higher EuroSCORE risk levels and higher NYHA status)
  • Retrospective design
  • Baseline differences between groups (MVR + CABG group had higher EuroSCORE and NYHA status)

Cite This Study

Ljubačev et al. (2013) conducted a cohort in Mitral regurgitation and ischemic heart disease (n=75). Mitral valve repair (MVRp) with concomitant CABG vs. Mitral valve replacement (MVR) with concomitant CABG was evaluated on In-hospital mortality, early postoperative morbidity, and length of stay. Mitral valve repair with concomitant CABG showed no statistically significant difference in in-hospital mortality compared to mitral valve replacement with CABG.

synapsesocial.com/papers/6a92e85d489c921ade771fbfhttps://doi.org/10.1080/00015458.2013.11680909
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