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April 12, 2004Annals of SurgeryOpen Access

Mitral Repair Is Superior to Replacement When Associated With Coronary Artery Disease

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Why the study?

Does mitral repair compared to mitral replacement improve hospital mortality and perioperative morbidity in patients with ischemic mitral regurgitation undergoing CABG?

Population

110 patients with ischemic mitral regurgitation undergoing combined coronary bypass and mitral procedures…

Comparison

Mitral valve repair combined with coronary… vs Mitral valve replacement with preservation of…

Design

Cohort

Follow-up

Hospital stay (perioperative)

Authors

TRT. Brett ReeceAmerican Heart AssociationCTCurtis G. TribbleUniversity of Virginia Health SystemPEPeter I. EllmanUniversity of Virginia

Discussion

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Implication

May favor repair to reduce mortality in ischemic MR with CABG; leaves open need for randomized confirmation.

Structured PICO

Does mitral repair compared to mitral replacement improve hospital mortality and perioperative morbidity in patients with ischemic mitral regurgitation undergoing CABG?

P
Population
110 patients with ischemic mitral regurgitation undergoing combined coronary bypass (CABG) and mitral procedures over a 7-year period. Mean age 67.0 in repair group and 69.2 in replacement group.
I
Intervention
Mitral valve repair combined with coronary artery bypass grafting (CABG)
C
Comparator
Mitral valve replacement (MVR) with preservation of the subvalvular apparatus combined with coronary artery bypass grafting (CABG)
O
Outcome
Hospital mortalityhard clinical

Mitral repair is associated with significantly lower hospital mortality compared to mitral replacement with subvalvular preservation in patients with ischemic mitral regurgitation undergoing concomitant CABG.

Cite This Study

Reece et al. (2004) studied this question.

synapsesocial.com/papers/6a72e6d582fd4d424b74870chttps://doi.org/10.1097/01.sla.0000124297.40815.86
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The effect of pathophysiology on the surgical treatment of ischemic mitral regurgitation: operative and late risks of repair versus replacement1995 · 206 citations
  2. 2Does Coronary Artery Bypass Grafting Alone Correct Moderate Ischemic Mitral Regurgitation?2001 · 354 citations
  3. 3Does the Additive Risk of Mitral Valve Repair in Patients With Ischemic Cardiomyopathy Prohibit Surgical Intervention?2000 · 49 citations
  4. 4Ultrasonic Echolucent Carotid Plaques Predict Future Strokes2001 · 578 citations