Key result
Open surgical repair of abdominal aortic aneurysms was associated with a significantly higher rate of early postoperative acute myocardial infarction compared to endovascular aneurysm repair (5.4% vs. 1.3%).
Why the study?
Does the type of AAA repair (OSR vs EVAR) and the presence of ischemic heart disease affect the risk of early postoperative acute myocardial infarction in patients undergoing elective abdominal aortic aneurysm repair?
Cohort (n=602)
No
Does the type of AAA repair (OSR vs EVAR) and the presence of ischemic heart disease affect the risk of early postoperative acute myocardial infarction in patients undergoing elective abdominal aortic aneurysm repair?
Absolute Event Rate: 5.4% vs 1.3%
p-value: p=0.012
In patients undergoing elective AAA repair, the risk of early postoperative myocardial infarction is significantly higher after open surgical repair compared to EVAR, and a positive preoperative functional stress test is a strong predictor of this complication.
Highlights need for cardiac optimization before open AAA repair; leaves open causal confirmation in randomized trials.
PURPOSE: We aimed to see the frequency of concomitant ischemic heart disease (IHD) in Korean patients with abdominal aortic aneurysm (AAA) and to determine risk factors for an early postoperative acute myocardial infarction (PAMI) after elective open or endovascular AAA repair. METHODS: We retrospectively reviewed a database of patients who underwent elective AAA repair over the past 11 years. Patients were classified into 3 groups: control group; group I, medical IHD treatment; group II, invasive IHD treatment. Rates of PAMI and mortality at 30 days were compiled and compared between groups according to the type of AAA repair. RESULTS: Six hundred two elective repairs of infrarenal or juxtarenal AAAs were enrolled in this study. The patients were classified into control group (n = 398, 66.1%), group I (n = 73, 12.1%) and group II (n = 131, 21.8%). PAMI developed more frequently after open surgical repair (OSR) than after endovascular aneurysm repair (EVAR) (5.4% vs. 1.3%, P = 0.012). In OSR patients (n = 373), PAMI developed 2.1% in control group, 18.0% in group I and 7.1% in group II (P < 0.001). In EVAR group (n = 229), PAMI developed 0.6% in control group, 4.3% in group I and 2.2% in group II (P = 0.211). On the multivariable analysis of risk factors of PAMI, PAMI developed more frequently in patients with positive functional stress test. CONCLUSION: The prevalence of concomitant IHD was 34% in Korean AAA patients. The risk of PAMI was significantly higher after OSR compared to EVAR and in patients with IHD compared to control group. Though we found some risk factors for PAMI, these were not applied to postoperative mortality rate.
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Han et al. (2016) conducted a cohort in Abdominal aortic aneurysm (AAA) (n=602). Open surgical repair (OSR) vs. Endovascular aneurysm repair (EVAR) was evaluated on Early postoperative acute myocardial infarction (PAMI) (p=0.012). Open surgical repair of abdominal aortic aneurysms was associated with a significantly higher rate of early postoperative acute myocardial infarction compared to endovascular aneurysm repair (5.4% vs. 1.3%).
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