Key result
In individuals with an exaggerated blood pressure response to exercise, low pulse pressure amplification was independently associated with lower early diastolic (P=0.019) and systolic (P=0.009) function.
Why the study?
Does low pulse pressure amplification (arterial stiffening) impair left ventricular function in individuals with an exaggerated blood pressure response to exercise?
Population
118 individuals, comprising 59 with an exaggerated blood pressure response to exercise and 59 age and…
Comparison
Low pulse pressure amplification after exercise vs High pulse pressure amplification after exercise…
Design
Cross-sectional
Authors
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Associated with impaired LV function in exercise hypertension; hypothesis-generating for arterial-ventricular interactions, needs prospective confirmation.
Case-Control (n=118)
Does low pulse pressure amplification (arterial stiffening) impair left ventricular function in individuals with an exaggerated blood pressure response to exercise?
Effect estimate: β = 0.16 for e'; β = 0.25 for S'
p-value: p=0.019 for e'; 0.009 for S'
In individuals with an exaggerated blood pressure response to exercise, concurrent arterial stiffening (low pulse pressure amplification) is associated with worse left ventricular diastolic and systolic function.
Shim et al. (2014) conducted a case-control in Exaggerated blood pressure response to exercise (n=118). Low pulse pressure amplification after exercise vs. High pulse pressure amplification after exercise was evaluated on Early diastolic (e') and systolic (S') mitral annular velocities (β = 0.16 for e'; β = 0.25 for S', p=0.019 for e'; 0.009 for S'). In individuals with an exaggerated blood pressure response to exercise, low pulse pressure amplification was independently associated with lower early diastolic (P=0.019) and systolic (P=0.009) function.
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