Key result
HIV infection was associated with significantly lower seroprevalence of poliovirus type 1 antibodies among pregnant females compared to HIV-negative females (91.8% vs 95.3%; PR 0.95; P<0.01).
Cross-Sectional (n=2,061)
Yes
Relative Risk: 0.95 (95% CI 0.92–0.98)
Absolute Event Rate: 91.8% vs 95.3%
p-value: p=<.01
Despite high overall poliovirus seroprevalence in pregnant Namibian women, HIV-positive individuals have significantly lower immunity to PV1 and PV3, highlighting a potential vulnerable population.
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HIV-positive pregnant women may have suboptimal polio immunity; leaves open whether catch-up vaccination improves protection in this population.
Cardemil et al. (2014) conducted a cross-sectional in Poliovirus immunity (n=2,061). HIV infection vs. HIV-negative status was evaluated on Seropositivity for poliovirus type 1 (PV1) antibody (PR 0.95, 95% CI 0.92-0.98, p=<.01). HIV infection was associated with significantly lower seroprevalence of poliovirus type 1 antibodies among pregnant females compared to HIV-negative females (91.8% vs 95.3%; PR 0.95; P<0.01).
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