Key result
Among unvaccinated Italian travelers aged 50-59 years, 100% had protective antibody titers against at least one poliovirus type, with seroprevalences of 86.7%, 89.9%, and 86.7% for types 1, 2, and 3.
Why the study?
What is the seroprevalence of anti-poliovirus antibodies in unvaccinated Italian travelers aged 50-59?
Population
98 unvaccinated Italian travelers aged 50 to 59 years from the Lombardy region
Design
Cross-sectional
Authors
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May inform selective polio vaccination for Italian travelers aged 50-59; leaves open generalizability and immunity duration.
Cross-Sectional (n=98)
No
What is the seroprevalence of anti-poliovirus antibodies in unvaccinated Italian travelers aged 50-59?
A high proportion of previously unvaccinated Italian adults aged 50-59 have protective immunity to polioviruses, which may impact cost-effectiveness analyses for generalized polio vaccination in adult travelers.
Signorini et al. (2004) conducted a cross-sectional in Unvaccinated travelers (n=98). Unvaccinated status was evaluated on Protective antibody titers against at least one of the three viral types. Among unvaccinated Italian travelers aged 50-59 years, 100% had protective antibody titers against at least one poliovirus type, with seroprevalences of 86.7%, 89.9%, and 86.7% for types 1, 2, and 3.
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