Why the study?
What is the seroprevalence of protective antibodies against polioviruses in the general population of Florence, Italy?
Population
328 sera from a convenience sample of the general population in Florence, Italy, collected in 2009
Design
Cross-sectional
Authors
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Low PV3 seroprevalence from age 11 may signal waning immunity; leaves open need for adolescent IPV boosters in Italy.
What is the seroprevalence of protective antibodies against polioviruses in the general population of Florence, Italy?
A significant proportion of the population in Florence, Italy, particularly from age 11 onwards, lacks protective antibodies against poliovirus type 3, supporting the recommendation for a fifth dose of IPV vaccine in adolescence.
Giammanco et al. (2018) studied this question.
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