Key result
The human platelet-derived endothelial cell growth factor (ECGF1) gene was localized to chromosome 22q13, placing it distal to the PDGFB locus at 22q12.3-q13.1.
Population
Human X rodent somatic cell hybrids and human chromosomes
Design
Preclinical
Authors
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No immediate clinical implications; leaves open ECGF1's functional role relative to PDGFB and requires validation studies.
This study maps the ECGF1 gene to chromosome 22q13, providing foundational genetic information about this growth factor.
Stenman et al. (2008) studied this question. The human platelet-derived endothelial cell growth factor (ECGF1) gene was localized to chromosome 22q13, placing it distal to the PDGFB locus at 22q12.3-q13.1.
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