Key result
Drug therapy, such as trimethaphan, increases survival in dissecting aortic aneurysm, though surgery may be required for complications or lack of response.
Why the study?
Does drug therapy improve survival in patients with dissecting aortic aneurysm?
Does drug therapy improve survival in patients with dissecting aortic aneurysm?
Drug therapy, such as trimethaphan, improves survival in dissecting aortic aneurysm by reducing aortic wall stress, though surgery may be required for complications or non-responders.
Drug therapy greatly increases the chances for survival in patients with dissecting aortic aneurysm. Trimethaphan is used to relieve stresses on the aortic wall by reducing the force of myocardial contraction and mean aortic pressure. Life-threatening complications or lack of response to drug therapy may necessitate surgery. Dissection occurs most frequently in the ascending aorta, and early mortality is higher in these cases than when only the descending aorta is involved.
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Lindsay et al. (1972) conducted a review in Dissecting aortic aneurysm. Drug therapy (Trimethaphan) and surgery was evaluated. Drug therapy, such as trimethaphan, increases survival in dissecting aortic aneurysm, though surgery may be required for complications or lack of response.
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