Key result
Among adult hypertensive patients, a family history of hypertension (AOR 2.8; 95% CI 1.8-4.3), smoking, physical inactivity, alcohol use, and heart disease were significant determinants of stroke.
Why the study?
Despite increasing hospital admissions for stroke due to hypertension, particularly in Ethiopia, studies exploring determinants of stroke among adult hypertensive patients were limited.
What are the determinants of stroke among adult hypertensive patients in Ethiopia?
Case-Control (n=525)
Yes
What are the determinants of stroke among adult hypertensive patients in Ethiopia?
Modifiable lifestyle factors and comorbidities are strong determinants of stroke among adult hypertensive patients in Ethiopia, highlighting the need for targeted preventive strategies.
Hypothesis-generating for stroke prevention in Ethiopian hypertensives; prospective studies needed to confirm causality and generalizability.
INTRODUCTION: Despite the increased admission of stroke patients in hospitals as a result of hypertension, especially in Ethiopia, there are limited studies that aim to explore important determinants of stroke, mainly among adult hypertensive patients. Therefore, this study was conducted to identify determinants of stroke among adult hypertension patients in Dessie Comprehensive Specialized Hospital and Kombolcha General Hospital, Amhara, Ethiopia. METHODS: An institutional-based case-control study design was conducted at Dessie Comprehensive Specialized Hospital and Kombolcha General Hospital from April 10, 2023, to May 30, 2023, on 105 cases and 420 controls selected by using a systematic random sampling technique. Data entry and processing were done using EPI-data version 4.4.2 and exported to SPSS version 26.0 for further analysis. Bi-variable and multi-variable logistic analysis was done to identify determinants of stroke among hypertension patients. Data were interpreted by using the odds ratio with a 95% confidence level, and a P-value < 0.05 was taken as statistically significant. RESULTS: A total of 105 cases and 420 controls participated in this study with a complete response (100%). Stroke among adult hypertension patients was significantly associated with a family history of hypertension (AOR = 2.8, 95% CI: 1.8-4.3), being physically inactive (AOR = 2.13, 95% CI: 1.4-3.3), current smoking cigarettes (AOR = 3.2, 95% CI: 2.1-5.2), current alcohol drinking (AOR = 4.7, 95% CI: 2.87-7.9), and having heart disease (AOR = 2.04, 95% CI: 1.3-3.25). CONCLUSIONS: Having a family history of hypertension, cigarette smoking, physical inactivity, alcohol consumption, and heart disease were determinants of stroke. Health education on lifestyle practices, early hypertension, and other cardiovascular diseases in each follow-up visit is very essential for improving stroke prevention.
No takes yet. Share an insight, caveat, or question.
Demile et al. (2025) conducted a case-control in Hypertension (n=525). Family history of hypertension vs. No family history of hypertension was evaluated on Stroke (AOR 2.8, 95% CI 1.8-4.3). Among adult hypertensive patients, a family history of hypertension (AOR 2.8; 95% CI 1.8-4.3), smoking, physical inactivity, alcohol use, and heart disease were significant determinants of stroke.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: