Carbamazepine-Induced Aseptic Meningitis

Brief Reports15 April 1990Carbamazepine-Induced Aseptic MeningitisLynn T. Simon, MD, Benjamin Hsu, MD, Bruce T. Adornato, MDLynn T. Simon, MD, Benjamin Hsu, MD, Bruce T. Adornato, MDAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-112-8-627 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptCarbamazepine is a drug increasingly used in a number of conditions including seizure disorders, trigeminal neuralgia, peripheral neuropathy, and occasionally psychiatric illness. We report a case of aseptic meningitis as an adverse effect of carbamazepine. The only previous report of this association is in a patient with the Sjögren syndrome.Case ReportA 50-year-old man with a history of bipolar illness, hypertension, diabetes, and right hemiparesis from a previous stroke presented to the Palo Alto Veterans Affairs Hospital on 8 May 1989 with confusion, left-sided myoclonus, temperature of 39 °C, and a diffuse erythematous maculopapular rash. The cerebrospinal fluid showed...References1. Pellock J. Carbamazepine side effects in children and adults. Epilepsia. 1987;28:S64-70. CrossrefMedlineGoogle Scholar2. Hilton E and Stroh E. Aseptic meningitis associated with administration of carbamazepine. J Infect Dis. 1989;159:363-4. CrossrefMedlineGoogle Scholar3. Widener H and Littman B. Ibuprofen-induced meningitis in systemic lupus erythematosus. JAMA. 1978;239:1062-4. CrossrefMedlineGoogle Scholar4. Bernstein R. Ibuprofen-related meningitis in mixed connective tissue disease. Ann Intern Med. 1980;92:206-7. LinkGoogle Scholar5. Kutt H. Interactions of antiepileptic drugs. Epilepsia. 1975;16:393-402. CrossrefMedlineGoogle Scholar6. Krag B, Dam M, Angelo H, and Christensen J. Influence of disulfiram on the serum concentration of carbamazepine in patients with epilepsy. Acta Neurol Scand. 1981;63:395-8. CrossrefMedlineGoogle Scholar7. Lippman S, Moskovitz R, and O'Tuama L. Tricyclic-induced myoclonus. Am J Psychiatry. 1977;134:90-1. CrossrefMedlineGoogle Scholar8. Aguglia U, Zappia M, and Quattrone A. Carbamazepine-induced nonepileptic myoclonus in a child with benign epilepsy. Epilepsia. 1987;28:515-8. CrossrefMedlineGoogle Scholar9. Ballenger J. The use of anticonvulsants in manic-depressive illness. J Clin Psychiatry. 1988;49(Suppl):S21-5. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Lynn T. Simon, MD; Benjamin Hsu, MD; Bruce T. Adornato, MDFrom Stanford University School of Medicine, Stanford, California. For current author addresses, see end of text. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPossible levetiracetam-induced aseptic meningitis versus viral meningitisDrug-induced meningitis: A review of the literature and comparison with an historical cohort of viral meningitis casesCarbamazepine-, Oxcarbazepine-, Eslicarbazepine-Associated Movement Disorder: A Literature ReviewDrug-Induced Aseptic Meningitis and Other MimicsLamotrigine-induced aseptic meningitis: a case reportDrug-induced aseptic meningitisMéningite aseptique médicamenteuse induite par le léflunomideLeflunomide-induced aseptic meningitisDrug-Induced Aseptic MeningitisCarbamazepineCarbamazepine Hypersensitivity Syndrome: Report of 4 Cases and Review of the LiteratureDrug-induced meningitisDrug- and Chemical-Induced Aseptic Meningitis: A Review of the LiteratureDrug-induced aseptic meningitis 15 April 1990Volume 112, Issue 8Page: 627-628KeywordsDermatologyDrugsEpilepsyHypertensionMeningitisMyoclonusPeripheral neuropathyRashesStrokeTemperature ePublished: 1 December 2008 Issue Published: 15 April 1990 PDF downloadLoading ...