Key result
Myocardial contrast echocardiography detected impaired coronary flow reserve in significant LAD stenosis, with a blunted increase in peak contrast intensity versus controls (3% vs 55%, P<0.01).
Why the study?
Can myocardial contrast echocardiography with intracoronary papaverine detect impaired coronary blood flow reserve in patients with significant LAD stenosis?
Population
21 consecutive patients undergoing coronary angiography with a single left anterior descending lesion or…
Comparison
Myocardial contrast echocardiography using… vs Baseline measurements and comparison between…
Design
Cross-sectional
Authors
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May support myocardial contrast echocardiography for coronary flow reserve assessment; hypothesis-generating and should not yet change practice.
Observational (n=21)
Can myocardial contrast echocardiography with intracoronary papaverine detect impaired coronary blood flow reserve in patients with significant LAD stenosis?
Absolute Event Rate: 3% vs 55%
p-value: p=<0.01
Myocardial contrast echocardiography can detect impaired coronary blood flow reserve in patients with significant LAD stenosis by demonstrating a failure of contrast parameters to increase after papaverine injection.
Reisner et al. (1992) conducted an observational in Coronary artery disease (n=21). Myocardial contrast echocardiography before and after intracoronary papaverine vs. Patients with normal or insignificant lesions (≤70% stenosis) was evaluated on Post-papaverine increase in peak contrast intensity (PCI) (p=<0.01). Myocardial contrast echocardiography detected impaired coronary flow reserve in significant LAD stenosis, with a blunted increase in peak contrast intensity versus controls (3% vs 55%, P<0.01).
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