Key result
Friable venous tumor thrombus consistency was associated with worse survival on univariate analysis but was not an independent predictor of survival in a multivariable model.
Why the study?
Does venous tumor thrombus consistency predict survival in patients with renal cell carcinoma?
Population
147 patients with renal cell carcinoma and a tumor thrombosis submitted to surgery from 2000 to 2013
Comparison
Assessment of venous tumor thrombus consistency vs Solid venous tumor thrombus consistency
Design
Cohort, Histological slides revised by two uropathologists blinded to clinical…
Follow-up
median 40.5 months
Authors
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Venous tumor thrombus consistency should not yet inform prognosis in renal cell carcinoma; leaves open its role in refined multivariable models.
Cohort (n=147)
Blinded outcome assessment
Does venous tumor thrombus consistency predict survival in patients with renal cell carcinoma?
Venous tumor thrombus consistency does not have an independent prognostic role for survival in patients with renal cell carcinoma.
Antonelli et al. (2015) conducted a cohort in Renal cell carcinoma with tumor thrombosis (n=147). Friable venous tumor thrombus consistency vs. Solid venous tumor thrombus consistency was evaluated on Survival (cancer-specific and overall). Friable venous tumor thrombus consistency was associated with worse survival on univariate analysis but was not an independent predictor of survival in a multivariable model.
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