Key result
Neck subcutaneous adipose tissue and abdominal visceral adipose tissue were significantly associated with increased carotid intima-media thickness, with neck fat being a strong predictor of subclinical atherosclerosis (beta coefficient 0.414, P=0.007).
Why the study?
Obesity is linked to cardiovascular diseases and body fat distribution correlates with subclinical atherosclerosis, prompting evaluation of how specific ultrasound-measured fat depots relate to carotid intima-media thickness in obese individuals.
Cross-Sectional (n=160)
No
Effect estimate: beta coefficient 0.414
p-value: p=0.007
Neck subcutaneous adipose tissue and abdominal visceral adipose tissue measured by ultrasound are significantly associated with subclinical carotid atherosclerosis, with NAT being a stronger predictor in women and VAT in men.
May support sex-specific adipose ultrasound for atherosclerosis risk assessment; hypothesis-generating for causality and outcomes.
Background: Obesity and overweight are major health problems associated with metabolic disorders and cardiovascular diseases. Body fat distribution is associated with subclinical atherosclerosis. The present study aimed to determine the association of abdominal visceral and subcutaneous fat and the neck subcutaneous fat, measured by ultrasound, with the intima-media thickness of the common carotid artery in obese individuals. Material and Methods: This study was performed on 160 individuals (82 men and 78 women; age: 20-70 years) to determine the association of abdominal visceral and subcutaneous fat and the neck subcutaneous fat as predictors of atherosclerosis based on ultrasound with the intima-media thickness of the common carotid artery. Results: Based on the multiple linear regression analysis results, the neck adipose tissue was generally a better predictor of subclinical atherosclerosis (P=0.007, beta coefficient=0.414). Besides, men had a higher visceral adipose tissue than women (P=0.003). It was found that the visceral adipose tissue (P=0.018, beta coefficient=0.537) in men and the neck adipose tissue (P=0.027, beta coefficient=0.472) in women were more strongly associated with the intima-media thickness.
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A 2023 study conducted a cross-sectional in Subclinical atherosclerosis (n=160). Regional adipose tissue (abdominal visceral, abdominal subcutaneous, and neck subcutaneous fat) was evaluated on Intima-media thickness (IMT) of the common carotid artery (beta coefficient 0.414, p=0.007). Neck subcutaneous adipose tissue and abdominal visceral adipose tissue were significantly associated with increased carotid intima-media thickness, with neck fat being a strong predictor of subclinical atherosclerosis (beta coefficient 0.414, P=0.007).
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