Key result
Perioperative hemodynamic optimization targeting supranormal oxygen delivery requires further study to determine its effect on gut ischemia, endotoxemia, and postoperative morbidity.
Why the study?
Does perioperative hemodynamic optimization reduce postoperative morbidity in high-risk surgical patients?
Does perioperative hemodynamic optimization reduce postoperative morbidity in high-risk surgical patients?
The authors propose that perioperative hemodynamic optimization to target supranormal oxygen delivery may reduce postoperative morbidity by mitigating gut ischemia and endotoxemia in high-risk surgical patients.
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Further trials needed before considering supranormal oxygen delivery targets; leaves open effects on gut ischemia, endotoxemia, and morbidity.
Wilson et al. (2001) conducted a review in High-risk surgery. Perioperative hemodynamic optimization was evaluated. Perioperative hemodynamic optimization targeting supranormal oxygen delivery requires further study to determine its effect on gut ischemia, endotoxemia, and postoperative morbidity.
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