Key result
Intraoperative plasma transfusion significantly increased the odds of postoperative deep vein thrombosis in patients undergoing malignant brain tumor resection (OR 6.85; 95% CI 2.73-17.18; P<0.001).
Why the study?
Patients with malignant brain tumors frequently exhibit hypercoagulation and are at high risk of thrombosis-related complications, but the specific postoperative risk factors remain unclear.
What are the risk factors for postoperative thrombosis-related complications in patients undergoing malignant brain tumor resection?
Population
456 elective patients undergoing resection of malignant brain tumors
Comparison
Patients with vs without postoperative thrombosis-related complications
Design
Retrospective observational cohort study
Authors
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May guide perioperative DVT risk stratification in brain tumor resection; hypothesis-generating pending prospective validation.
Cohort (n=456)
What are the risk factors for postoperative thrombosis-related complications in patients undergoing malignant brain tumor resection?
Odds Ratio: 6.85 (95% CI 2.73–17.18)
p-value: p=<0.001
Age over 60, abnormal APTT, prolonged surgery, ICU admission, and intraoperative plasma transfusion are independent risk factors for postoperative DVT in patients undergoing malignant brain tumor resection.
Liu et al. (2023) conducted a cohort in Malignant brain tumors (n=456). Intraoperative plasma transfusion vs. No intraoperative plasma transfusion was evaluated on postoperative deep vein thrombosis (OR 6.85, 95% CI 2.73-17.18, p=<0.001). Intraoperative plasma transfusion significantly increased the odds of postoperative deep vein thrombosis in patients undergoing malignant brain tumor resection (OR 6.85; 95% CI 2.73-17.18; P<0.001).
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