Key result
A positive ED CK-MB in patients with chest pain without ST-segment elevation was associated with a significantly increased risk of any ischemic complication (RR 16.1; 95% CI 11.0-23.6).
Why the study?
Does a positive CK-MB in the emergency department predict ischemic complications in patients admitted for chest pain without ST-segment elevation?
Population
5,120 patients admitted to the hospital for evaluation of chest pain without ST-segment elevation on the…
Comparison
Positive CK-MB level in the emergency department vs Negative CK-MB level in the emergency department
Design
Cohort
Follow-up
In-hospital
Authors
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May aid ED risk stratification in non-ST-elevation chest pain; leaves open prospective validation before guiding care.
Cohort (n=5,120)
Yes
Does a positive CK-MB in the emergency department predict ischemic complications in patients admitted for chest pain without ST-segment elevation?
Relative Risk: 16.1 (95% CI 11–23.6)
Elevated CK-MB in the emergency department strongly predicts ischemic complications and death in patients presenting with chest pain without ST-segment elevation.
Hoekstra et al. (1994) conducted a cohort in Chest pain without ST-segment elevation (n=5,120). Positive ED CK-MB vs. Negative ED CK-MB was evaluated on Any ischemic complication (RR 16.1, 95% CI 11.0-23.6). A positive ED CK-MB in patients with chest pain without ST-segment elevation was associated with a significantly increased risk of any ischemic complication (RR 16.1; 95% CI 11.0-23.6).
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