Accidental contagion of poliomyelitis virus occurred in two uninoculated chimpanzees quartered near inoculated rhesus monkeys, evidenced by virus isolation and antibody development after 6 months.
Case Report (n=2)
Poliomyelitis virus was isolated from the stools of two uninoculated chimpanzees which had been quartered for 6 months in cages adjoining those of rhesus monkeys receiving intranasal inoculations of potent human stools. Upon arrival, and for 4 months thereafter, neither chimpanzee had antibody against the virus eventually isolated from it. However, antibody had developed against the animals' own virus strains at the time these were isolated from the feces.
Howe et al. (1944) conducted a case report in Poliomyelitis (n=2). Accidental contagion (proximity to inoculated monkeys) was evaluated on Isolation of poliomyelitis virus and development of antibodies. Accidental contagion of poliomyelitis virus occurred in two uninoculated chimpanzees quartered near inoculated rhesus monkeys, evidenced by virus isolation and antibody development after 6 months.
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