Key result
Sevoflurane significantly accelerated emergence compared to isoflurane in geriatric patients undergoing laparoscopic cholecystectomy, reducing time to spontaneous breathing from 4.38 to 2.33 minutes (p<0.001).
Why the study?
The study was conducted to compare the effects of sevoflurane and isoflurane on hemodynamics and recovery characteristics in geriatric patients undergoing laparoscopic cholecystectomy.
Does sevoflurane improve recovery characteristics compared to isoflurane in geriatric patients undergoing laparoscopic cholecystectomy?
RCT (n=80)
Single-blind
Randomized
No
Does sevoflurane improve recovery characteristics compared to isoflurane in geriatric patients undergoing laparoscopic cholecystectomy?
Sevoflurane provides significantly faster emergence and recovery times compared to isoflurane in geriatric patients undergoing laparoscopic cholecystectomy, while maintaining comparable hemodynamic stability.
Answers are grounded in this paper and cite their sources.
Sevoflurane may offer faster recovery than isoflurane in geriatric LC with stable hemodynamics; leaves open need for larger trials before practice change.
Objective: The aim of the present study was to compare sevoflurane and isoflurane on hemodynamics and recovery characteristics in geriatric patients undergoing laparoscopic cholecystectomy (LC). Methods: The prospective, comparative, and randomized study was conducted on a total of 80 patients aged above 60 years of either sex and American Society of Anesthesiologists physical status I and II who were scheduled for elective LC under general anesthesia in Government Medical College, Rajindra Hospital, Patiala. Results: Patients were hemodynamically stable throughout the surgery in both the groups but the emergence and recovery were significantly faster in the sevoflurane group. The sevoflurane group showed a faster time to spontaneous breathing, time to eye-opening, response to verbal commands, extubation time, and early orientation of the patient. Conclusion: Sevoflurane might be considered a useful alternative to isoflurane in providing anesthesia in laparoscopic cholecystectomies, especially in elderly patients where rapid emergence and recovery are very much desired along with stable hemodynamic parameters.
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KUMAR et al. (2024) conducted an RCT in Laparoscopic cholecystectomy (n=80). Sevoflurane vs. Isoflurane was evaluated on Time to spontaneous breathing (p=<0.001). Sevoflurane significantly accelerated emergence compared to isoflurane in geriatric patients undergoing laparoscopic cholecystectomy, reducing time to spontaneous breathing from 4.38 to 2.33 minutes (p<0.001).
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