Key result
A high serum IL-10 level (≥30 pg/ml) was independently predictive of increased 30-day mortality (OR 34.79) in patients with ST-segment elevation acute myocardial infarction undergoing primary PCI.
Why the study?
Does a high serum IL-10 level predict increased 30-day mortality in patients with ST-segment elevation acute myocardial infarction undergoing primary PCI?
Cohort (n=250)
No
Does a high serum IL-10 level predict increased 30-day mortality in patients with ST-segment elevation acute myocardial infarction undergoing primary PCI?
Odds Ratio: 34.79 (95% CI 7.9–153.23)
Absolute Event Rate: 35.3% vs 3%
p-value: p=<0.0001
In patients with ST-segment elevation myocardial infarction undergoing primary PCI, a high serum IL-10 level (≥30 pg/ml) is a strong independent predictor of 30-day mortality.
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Should not yet guide STEMI risk stratification; leaves open whether IL-10 adds to existing models.
Yip et al. (2007) conducted a cohort in ST-segment elevation acute myocardial infarction (n=250). High serum IL-10 level (≥30 pg/ml) vs. Low serum IL-10 level (<30 pg/ml) was evaluated on 30-day mortality (OR 34.79, 95% CI 7.90-153.23, p=<0.0001). A high serum IL-10 level (≥30 pg/ml) was independently predictive of increased 30-day mortality (OR 34.79) in patients with ST-segment elevation acute myocardial infarction undergoing primary PCI.
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