Key result
Non-linear analysis of EEG signals distinguished children with ADHD from normal cases with 98% sensitivity, 92.31% specificity, and 96.05% accuracy.
Why the study?
Early diagnosis of ADHD is crucial to reduce harmful effects, and chaotic indices from non-linear EEG analysis can be employed to distinguish ADHD from normal children.
Does non-linear analysis of EEG signals accurately distinguish ADHD from normal children?
Case-Control (n=76)
Does non-linear analysis of EEG signals accurately distinguish ADHD from normal children?
Non-linear analysis of EEG signals from the frontal lobe provides high accuracy in distinguishing children with ADHD from normal children.
Non-linear EEG analysis may aid early ADHD diagnosis; leaves open prospective validation before clinical adoption.
Attention deficit hyperactivity disorder (ADHD) is a common behavioural disorder that may be found in 5%-8% of the children. Early diagnosis of ADHD is crucial for treating the disease and reducing its harmful effects on education, employment, relationships, and life quality. On the other hand, non-linear analysis methods are widely applied in processing the electroencephalogram (EEG) signals. It has been proved that the brain neuronal activity and its related EEG signals have chaotic behaviour. Hence, chaotic indices can be employed to classify the EEG signals. In this study, a new approach is proposed based on the combination of some non-linear features to distinguish ADHD from normal children. Lyapunov exponent, fractal dimension, correlation dimension and sample, fuzzy and approximate entropies are the non-linear extracted features. For computing, the chaotic time series of obtained EEG in the brain frontal lobe (FP1, FP2, F3, F4, and Fz) need to be analysed. Experiments on a set of EEG signal obtained from 50 ADHD and 26 normal cases yielded a sensitivity, specificity, and accuracy of 98, 92.31, and 96.05%, respectively. The obtained accuracy provides a significant improvement in comparison to the other similar studies in identifying and classifying children with ADHD.
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Boroujeni et al. (2019) conducted a case-control in Attention deficit hyperactivity disorder (ADHD) (n=76). Non-linear analysis of EEG signals vs. Normal cases was evaluated on Diagnosis of ADHD. Non-linear analysis of EEG signals distinguished children with ADHD from normal cases with 98% sensitivity, 92.31% specificity, and 96.05% accuracy.
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