Answers are grounded in this paper and cite their sources.
Obesity worldwide is a concern due to its link with an increased prevalence of NAFLD.1 This issue is prevalent in obese children with high-fat diet (HFD).2 Recent studies have shown that NAFLD is associated with dysbiosis and increased intestinal permeability.3,4 Zonulin, a regulator and effective tight junction (TJ) permeability biomarker, is known to loosen TJs, leading to increased intestinal permeability.3,5–9.
No takes yet. Share an insight, caveat, or question.
Huang et al. (2025) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: