Key result
Temporary blockage of blood flow via cuff inflation did not significantly influence the peripheral vascular pulse wave velocity in healthy individuals (mean difference 0.114, p=0.475).
Observational (n=10)
No
Bioimpedance plethysmography combined with ECG provides a method to estimate peripheral pulse wave velocity, which is independently predicted by anthropometric and blood pressure parameters.
Cuff inflation does not affect peripheral PWV in healthy subjects; leaves open validation of bioimpedance-ECG PWV estimation in clinical populations.
In this study, a simple bioimpedance plethysmography method was employed to measure the pulse wave velocity (PWV) from the radial artery in the wrist to the middle finger of a patient. Subsequently, electrocardiography was combined with a bioimpedance method to calculate the PWV from ECG and pulse waves to the middle finger. Experiments were conducted by employing cuffs that temporarily block blood flow to produce observable changes in the PWV. Statistical results indicated that temporary blockage of blood flow did not influence the PWV of typical healthy people. Moreover, multiple regression analysis was used to establish an equation for estimating two types of PWV and their relevance with other physiological parameters. Multiple regression analysis indicated that the abdomen circle and height are independent predictors of the PWV from the radial artery in the wrist to the middle finger (wfPWV) (r = 0.893). Systolic blood pressure (SBP) and diastolic blood pressure (DBP) are independent predictors of the PWV from the EGC T wave to the middle finger (tfPWV) (r = 0.898). Correlation analysis showed the wfPWV is significantly associated with tfPWV (r = 0.770, p < 0.01).
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Huang et al. (2017) conducted an observational in Healthy (n=10). Temporary blood flow blockage via cuff inflation vs. Baseline (before cuff inflation) was evaluated on Pulse wave velocity from the radial artery in the wrist to the middle finger (wfPWV) (MD 0.114, 95% CI -0.233 to 0.462, p=0.475). Temporary blockage of blood flow via cuff inflation did not significantly influence the peripheral vascular pulse wave velocity in healthy individuals (mean difference 0.114, p=0.475).
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