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December 1, 2020Artery ResearchOpen Access

Radial-digital pulse wave velocity can non-invasively assess small artery stiffness, with a 10 mm Hg increase in local mean arterial pressure resulting in a 0.28 m/s increase in RD-PWV.

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Why the study?

Does radial-digital pulse wave velocity (RD-PWV) provide a feasible non-invasive measure of peripheral small artery stiffness in healthy subjects?

Population

29 healthy subjects

Design

Cross-sectional

Key result

Radial-digital pulse wave velocity can non-invasively assess small artery stiffness, with a 10 mm Hg increase in local mean arterial pressure resulting in a 0.28 m/s increase in RD-PWV.

Authors

HOHasan ObeidCGCharles-Antoine GarneauCFCatherine Fortier

Discussion

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Overview

RD-PWV may enable small-artery stiffness assessment; leaves open clinical utility and validation in patients.

Study Design

Type

Cross-Sectional (n=29)

Structured PICO

Does radial-digital pulse wave velocity (RD-PWV) provide a feasible non-invasive measure of peripheral small artery stiffness in healthy subjects?

P
Population
29 healthy subjects evaluated for radial-digital pulse wave velocity to assess small artery stiffness.
E
Exposure
Radial-digital pulse wave velocity (RD-PWV) measurement using Complior probes and various transit time algorithms (device-embedded, Matlab-based, numerical simulation)
O
Outcome
RD-PWV values, correlation between algorithms, intersession coefficients of variation, and response to changes in local mean arterial pressuresurrogate

Main Result

Effect estimate: 0.28 m/s increase per 10 mm Hg increase in MAP

Radial-digital pulse wave velocity is a feasible and responsive non-invasive method for assessing the stiffness of peripheral small arteries.

Cite This Study

Obeid et al. (2020) conducted a cross-sectional in Healthy (n=29). Radial-digital pulse wave velocity (RD-PWV) was evaluated on Radial-digital pulse wave velocity (RD-PWV) response to changes in local mean arterial pressure (0.28 m/s increase per 10 mm Hg increase in MAP). Radial-digital pulse wave velocity can non-invasively assess small artery stiffness, with a 10 mm Hg increase in local mean arterial pressure resulting in a 0.28 m/s increase in RD-PWV.

synapsesocial.com/papers/6aacfab632841ec54fd492fehttps://doi.org/10.2991/artres.k.201209.038
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