Review: Synthesis of Nano Bioactive Glass or Bioglass

Currently, bioglass nanoparticles are one of the most developed nanotechnology materials due to their bioactive properties and mechanical work which can be widely applied, especially in biomedical fields such as bone tissue engineering and orthopedic implants. Writing this paper is aimed at conducting a literature review on the synthesis of bioglass nanoparticles. In this paper, we review 40 papers from 2001 to 2020. From several papers that have been reviewed, several methods can be used to make bioglass nanoparticles, including melt quenching, sol-gel, sol-gel with acid media, sol-gel using the OMC 3D template OMC, sol-gel using the DDA template, sol-gel using the P123 pluronic copolymer template, sol-gel with Cu doping, sol-gel using silver ion and fluoride doping, sol-gel from rice husk, microwave irradiation, flame synthesis, and microemulsion. The best method of nanoparticles bioglass synthesis is sol-gel using OMC 3D template for produce particles with a size of about 300 nm which is smaller than the size of the OMC 3D template, the surface area of 26 m2/g, and no agglomeration of particles observed by TEM and DLS.