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HFIP has developed immense importance in the C–H functionalization methodology. Both the reactivity and selectivity have been vastly improved using HFIP whose H-bonding to the substrate facilitates and accelerates C–H activation. This review summarizes the chronological development of the evolution of HFIP in C–H activation along with important mechanistic details.
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Sinha et al. (2018) studied this question.
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