Key result
Specific alpha 1 postsynaptic adrenoceptor blocking drugs have become available to treat hypertension, with their efficacy, tolerance, and acceptability discussed in this review.
Why the study?
What is the role of specific alpha 1 postsynaptic adrenoceptor blocking drugs in the treatment of hypertension?
What is the role of specific alpha 1 postsynaptic adrenoceptor blocking drugs in the treatment of hypertension?
This review highlights the development and clinical utility of specific alpha 1 postsynaptic adrenoceptor blocking drugs for the treatment of hypertension.
Early attempts to use alpha-adrenoceptor blockers in the treatment of hypertension were unsuccessful due to a high prevalence of side-effects. Now that the concept of two alpha-adrenoceptors, alpha 1 and alpha 2 has been investigated, specific alpha 1 postsynaptic adrenoceptor blocking drugs have become available to treat hypertension. Their efficacy, tolerance and acceptability are discussed, and indications for their usage suggested.
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Abrams et al. (1983) conducted a review in Hypertension. Alpha 1 postsynaptic adrenoceptor blocking drugs was evaluated. Specific alpha 1 postsynaptic adrenoceptor blocking drugs have become available to treat hypertension, with their efficacy, tolerance, and acceptability discussed in this review.
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