Key result
Among patients treated with EVAR for abdominal aortic aneurysm, early conversion to open surgery occurred in 1.5% (mortality 12.4%) and late conversion in 1.9% (mortality 10%).
Why the study?
What is the incidence and mortality of conversion to open surgery after endovascular aneurysm repair for abdominal aortic aneurysm?
Systematic Review (n=14,298)
What is the incidence and mortality of conversion to open surgery after endovascular aneurysm repair for abdominal aortic aneurysm?
Conversion to open surgery after EVAR for AAA is uncommon (1.5-1.9%) but carries a high mortality rate of 10-12%, underscoring the need for lifelong surveillance.
High mortality despite low conversion rates after EVAR warrants lifelong surveillance; extends pooled risk estimates for patient counseling.
PURPOSE: To review the incidence, causes, and mortality rates of early and late conversion to open surgery after endovascular aneurysm repair (EVAR) of abdominal aortic aneurysm (AAA). METHODS: A systematic search of the English-language literature from 2002 to 2009 was performed by interrogation of the PubMed, MEDLINE, and EMBASE databases. Studies were included if they: (1) had >100 patients treated with EVAR and (2) provided adequate data to calculate incidence and associated mortality rates. The search yielded 13 articles with sufficient data to analyze early conversion (12,236 patients, 178 conversions) and 15 articles with available data for late conversion (14,298 patients, 279 conversions). RESULTS: The rate of early conversion among the 13 articles reviewed ranged from 0.8% to 5.9%; more recent studies carried lower rates of early conversion. Mortality rates of early conversion varied between 0% and 28.5%. Overall, there were 178 (1.5%) early conversions among the 12,236 AAAs treated with EVAR, with an average mortality of 12.4%. The rates of late conversion ranged from 0.4% to 22%. Of the 14,289 AAA patients undergoing endovascular repair, 279 (1.9%) required late conversion; the mortality rate was 10%. CONCLUSION: Though the incidence is gradually declining, secondary interventions persist as the Achilles' heel of EVAR. A lifelong follow-up strategy for AAA patients treated with EVAR is essential for early detection and treatment of complications of the procedure. Vascular surgeons should be familiar with the complex open conversion procedures.
No takes yet. Share an insight, caveat, or question.
Moulakakis et al. (2010) conducted a systematic review in Abdominal aortic aneurysm (AAA) (n=14,298). Endovascular aneurysm repair (EVAR) was evaluated on Early and late conversion to open surgery. Among patients treated with EVAR for abdominal aortic aneurysm, early conversion to open surgery occurred in 1.5% (mortality 12.4%) and late conversion in 1.9% (mortality 10%).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: