Key result
Late open surgical conversion after EVAR had an overall 30-day mortality rate of 16.12%, with urgent conversion identified as a predictor for 30-day mortality.
Why the study?
Increasing numbers of EVAR procedures lead to more patients requiring late open surgical conversion, prompting an analysis of elective versus urgent LOSC outcomes and predictors.
What are the outcomes and predictors of 30-day mortality for late open surgical conversion after EVAR in elective versus urgent settings?
Observational (n=31)
Yes
What are the outcomes and predictors of 30-day mortality for late open surgical conversion after EVAR in elective versus urgent settings?
Late open surgical conversion after EVAR is relatively safe when performed electively, but urgent conversion is associated with high mortality, primarily driven by myocardial infarction.
Emphasizes risks of urgent late conversion post-EVAR; leaves open optimal surveillance and timing strategies.
BACKGROUND: Accumulated endovascular aneurysm repair (EVAR) procedures will increase number of patients requiring conversion to open repair of abdominal aortic aneurysms (AAA). In most cases, patients undergo late open surgical conversion (LOSC), many months, or years, after initial EVAR. The aim of this study is to analyze results of LOSC after EVAR in elective and urgent setting, including presenting features, surgical techniques, as well as to review the clinical outcomes and their predictors. METHODS: Retrospective review of all consecutive patients undergoing LOSC after EVAR was performed at three distinct, high volume, vascular centers. Patients that required primary conversion within 30 days after EVAR have not been included in this study. Between January 1st 2010 and January 1st 2017 total of 31 consecutive patients were treated. LOSC were performed either in elective or in urgent setting, thus dividing patients in two groups. Primary outcome was 30-day mortality and secondary postoperative complications. RESULTS: LOSC rate after EVAR was 4.51%. Most common indication for LOSC was type I endoleak (N.=20, 64.51%). All patients that presented with ruptured AAA had some form of endoleak (type I endoleak was present in five from six cases). Most common site for aortic cross-clamping was infrarenal (51.61%). Stent-graft was removed completely in 18 patients (58.06%) and partially in 13 (41.93%). 30-day mortality rate was 16.12% (5 patients) and most common cause of death was myocardial infarction (60%). Following univariate factors were isolated as predictors for 30-day mortality: preoperative coronary artery disease, chronic obstructive pulmonary disease, urgent LOSC, prolonged time until LOSC, ruptured AAA, supraceliac clamp, higher number of red blood cell transfusion, postoperative myocardial infarction, and prolonged intubation (more than 48 hours). CONCLUSIONS: LOSC seems to be safe and effective procedure when preformed in elective manner. On the other side, urgent LOSC after EVAR is associated with very high postoperative mortality and morbidity. Endoleak remains the main indication for open conversion. Further studies are necessary to standardize timing and treatment options for failing EVAR.
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Davidović et al. (2020) conducted an observational in Abdominal aortic aneurysm requiring late open conversion after EVAR (n=31). Late open surgical conversion (LOSC) vs. Elective vs urgent setting was evaluated on 30-day mortality and secondary postoperative complications. Late open surgical conversion after EVAR had an overall 30-day mortality rate of 16.12%, with urgent conversion identified as a predictor for 30-day mortality.
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